"Researchers have found that people with type 2 diabetes were more than 80% more likely to be later diagnosed with Parkinson's disease than people without diabetes. This is the first study to suggest that diabetes may be a risk factor of Parkinson's disease, a progressive disease that causes muscle rigidity and tremors."

"The study followed a group of more than 50,000 men and women over a period of 18 years. During that time, 324 men and 309 women developed Parkinson's disease. People who had type 2 diabetes at the start of the study were far more likely to be later diagnosed with Parkinson's disease. Overall, after adjusting for other possible risk factors for Parkinson's disease, men and women with type 2 diabetes were 83% more likely to develop Parkinson's disease than those without it."

"Although the exact nature of the relationship between diabetes and Parkinson's disease is unclear, researchers say several lifestyle factors may be associated with both disorders. Among these factors are: obesity, cigarette smoking, and lack of physical activity."

"Perhaps further research between the association of diabetes and Parkinson's disease could help researchers better understand an avenue to a cure. . Pioglitazone is a drug used to treat diabetes. It may also help fight the onset of Parkinson's. Thanks to funding from The Michael J. Fox Foundation "

"1. A. In respect of the comment: â??â?¦Researchers have found that people with type 2 diabetes were more than 80% more likely to be later diagnosed with Parkinson's disease than people without diabetes â?¦ Pioglitazone is a drug used to treat diabetesâ?¦â?"

"How true is the statement above (?) or is the following statement more accurate: â??Researchers have found that people with type 2 diabetes [AND UNDERGOING drug/insulin TREATMENT] were more than 80% more likely to be later diagnosed with Parkinson's disease than people without diabetesâ???"

"Please provide details of exactly where the abovementioned research has been published / â??Peer reviewedâ?? so that the abovementioned important distinction can be checked upon [because the reported side-effects for Pioglitazone, a drug used to â??treatâ?? type 2 diabetes, are: hypoglycemia, EDEMA, upper respiratory tract infection, anaemia, headache, sinusitis, myalgia, tooth disorder, diabetes mellitus aggravated, pharyngitis, reduction of haemoglobin, hematocrit and bilirubin]â?¦"

"Transient supernormal glycaemia â??TSGâ?? occurs in every Human Being as a healthy and natural response to stress [â??adaptive medicineâ??] and may well increase HgA1c â?¦ so what? â?¦ when glucose levels surge up for a transient period [and then down again] an above average HgA1c can just as easily be viewed as a marker for a very healthy â??stress adaptedâ?? Human Being who has the benefit of being â??insulin-resistantâ?? ie a criteria for being labelled a â??type 2 Diabeticâ??; and"

"B. What is the most definitive study which substantiates the benefit of reducing HgA1c in drug/insulin treated acute&chronic 'insulin-resistant diabetes' [Type 2] â?¦ as compared with treatment-free [drug/insulin] acute&chronic 'insulin-resistant diabetes' [ie in a ZERO drug (repeat zero) treatment control Group]? {ps please note the word written there says: â??zeroâ?} ie completely ignoring HgA1c value variabilityâ?¦"

"... Am seeking a â??Peer reviewedâ?? study that clearly disassociates drug/insulin treatment from any changes in Patient behaviour [eg diet/exercise] and/or categorically proves that drug/insulin treated acute&chronic 'insulin-resistant diabetes' is healthier than doing absolutely nothing [â??zeroâ??] ie just accepting the higher HgA1c value and [possibly beneficial] blood glucose value [and possibly beneficial â??insulin resistanceâ?]; and"

"C. What is the most definitive study which provides incontrovertible evidence that the apparent insulin receptor mediated down-regulation [in response to: transient supernormal glycaemia â??TSGâ??] is anything substantially other than a stress-adaptive mechanism of 'local' [on a cell-by-cell basis] intracellular cyto-protection from influx of excessive [blood] circulating glucose [ie homeostasis] eg cardio muscle protective?"

"... My understanding is that insulin receptor mediated down-regulation â??IRDâ?? [aka â??insulin resistanceâ?] is primarily an adaptive [protective/regulatory/beneficial] reply to transient [and chronically repeated] oral indulgence/stress â?¦"

"eg "...healthy young students were fed a very high fat diet containing egg yolks, heavy cream, and butter, and within 2 days all of the students had blood sugar
... read the whole article