"The study included 13 elderly men and women with MCI and a control group of 14 elderly people with no memory problems. Researchers used positron emission tomography (PET) scans to measure uptake of an imaging agent called PIB that highlights abnormal protein aggregation growth, or amyloid plaque, in the brain. A build-up of amyloid plaque is a signature of Alzheimer's disease."

"The scans revealed that the people with MCI had as much as 39 percent more PIB uptake in some areas of the brain than those in the control group. About half of the people with MCI had PIB uptake levels indicative of Alzheimer's disease."

""This pattern of increased PIB in patients with MCI resembles
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